Wednesday 11 September 2013

FAQ with Epilepsy and the role of Glutathione

What is Epilepsy?


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Epilepsy is a chronic neurological disorder characterised by brain seizures, resulting from abnormal neuronal activity in the brain.

Often the seizures will occur spontaneously, however sometimes certain precipitants can trigger a seizure. Examples of triggers for epilepsy may include emotional stress, air pollution, sleep deprivation, medications, alcohol and radiation. These are all factors that are known to reduce levels of glutathione, a vital brain antioxidant.

Seizures create a huge amount of oxidative stress which is very damaging to the brain cells, further reducing the glutathione levels.

The damaging free radicals that are formed during a seizure diminish levels of glutathione in the brain. Anti-seizure drugs also have the undesirable side effect of reducing glutathione levels. 

Epilepsy and Glutathione


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Glutathione is an important neuromodulator that directly affects the activity of brain cells.

Research scientists in Japan, Canada and Italy have conducted independent experiments showing that drug induced seizures can be prevented if glutathione is administered beforehand.

Canadian scientists demonstrated that a combined therapy of glutathione with antioxidant vitamin E reduced the number of brain cells damaged after a seizure.

Several scientists have successfully used glutathione precursors to treat seizures.

Dr Jimmy Gutman states in his book Glutathione: Your Key to Health  "Since glutathione is also itself an anticonvulsant, it may be used as a complementary therapy to both treat and prevent seizures as well as to lessen the adverse effects of conventional drugs.” 

The Power of Cellgevity

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Increased levels of intracellular glutathione will help to neutralise the harmful free radicals created during a seizure, and may even help to prevent seizures.  
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Can Glutathione Help With Seizures?

Answer:

Yes. Here's why:

Notice what Dr. Jimmy Gutman, world-renowned expert on the subject of glutathione, has to say in his latest bestseller, "Glutathione - Your Key To Health", page 188:

"Since glutathione directly affects the activity of brain cells, it is called a neuromodulator. Japanese scientists K. Abe, K. Nakanishi and H. Saito protected animals from drug-induced seizures by injecting glutathione directly into the fluid of the brain and spinal cord.

Canadians at Toronto Western Hospital showed that combined vitamin E and glutathione reduced the number of brain cells damaged after seizure activity. In Texas, S.G. Jenkinson, J.M. Jordan and C.A. Duncan were able to protect laboratory animals from seizures and death by injecting them with glutathione, and Italians at the University of Milansuccessfully prevented seizures caused by Isoniazid - a tuberculosis medication - by administering patients with glutathione beforehand.

Several scientists have used N-acetylcysteine (NAC, see Chapter 4) , a powerful glutathione precursor, to treat seizures, and Swedish researchers led by E. Ben-Menachem applied it to patients suffering from progressive myoclonic epilepsy - a particularly hard-to-treat disease that gradually destroys the nervous system. Patients given a daily dose of 6 grams showed marked improvements, and an American team from Gainesville, Florida used NAC, vitamin E, B2, zinc, and selenium to treat this type of seizure, obtaining similar improvements.

Free radical formation and oxidative stress can be seen as both a cause and a result of seizures, and conditions that diminish glutathione levels - including the use of anti-seizure drugs themselves - may well lower glutathione levels as well. 

Since glutathione is also itself an anticonvulsant, it may be used as a complementary therapy to both treat and prevent seizures as well as to lessen the adverse effects of conventional drugs."

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